Cephalon recently issued letters to healthcare providers that Provigil can cause life-threatening skin disease including Stevens-Johnson Syndrome. Provigil is a medication for adults who suffer from excessive sleepiness. Common users are adults who have narcolepsy, obstructive sleep apnea/hypopnea syndrome, and shift work sleep disorder. Cephalon has revised its warning to instruct patients to discontinue use if they develop a rash or have other hypersensitivity reactions. In addition, psychiatric symptoms were noted in some patients who took this drug.
For more information on this subject please refer to the section on Drugs, Medical Devices, and Implants.